Ciudad Dario can be reached by the Pan American highway. The city is located on the Km 90, where you will see the entrance to the municipality with signs and a statue of Rubén Darío. Ciudad Darío has direct and frequent buses traveling to Matagalpa. Public transportation to the cities of Northern Nicaragua pass by the entrance of it.
When in Managua, you have to go to the Mayoreo Market and take a bus with direction to Matagalpa, Estelí, Ocotal o Somoto. Ask the driver to drop you off at the entrance of Ciudad Darío.